Dehydrated skin study, 2020

Trial centre

Complife Italia S.r.l, Italy.

Study 1: Stratum corneum hydration and barrier function

Objective

To assess the efficacy of a single application of Bio‑Oil Skincare Oil (Natural) to
improve stratum corneum hydration and barrier function.

Sample
Subjects: 40 female participants of varying ethnicities. Test site: test product
applied to the inner volar forearm of all subjects. Age of participants: over 18
years old.

Methodology

A randomised, blinded and controlled study. Assessment of skin hydration with
a Corneometer, assessment of barrier function with a Tewameter. Participants
washed their forearms with soap 2 hours before measurements were taken in
order to induce skin dryness. Baseline instrumental measurements were taken.
Bio‑Oil Skincare Oil (Natural) was then applied to a site on the inner volar forearm
of all subjects. Measurements were taken again immediately after product
application as well as 1 and 2 hours later, before and after wiping the product off.
A control untreated site was also measured at all time points.

Result

Bio‑Oil Skincare Oil (Natural) treatment resulted in a significant improvement of
skin moisturisation and a significant decrease of transepidermal water loss (an
index of improvement in skin barrier condition) at each experimental monitored
check, compared to dehydrated skin.

Study 2: Appearance of dry skin

Objective

To assess the efficacy of Bio‑Oil Skincare Oil (Natural) in improving the
appearance of dry skin.

Sample

Subjects: 25 female Caucasian participants clinically showing dry/very dry
desquamated skin at the level of the outer lower legs. Test site: test product
applied to the outer, lower leg of all subjects. Age of participants: 25—65 years
old.

Methodology

A randomised, double blinded and controlled clinical-instrumental study. Clinical
evaluations of dry skin were performed by a trained visual evaluator, assessment
of skin hydration with a Corneometer and assessment of barrier function with a
Tewameter. Participants washed their legs with soap to induce dry skin over a
7-day period. Baseline instrumental measurements were taken. Bio‑Oil Skincare
Oil (Natural) was applied twice daily. Clinical assessments and instrumental
evaluations were made on days 1 and 3. A control untreated site was also
evaluated at all time points.

Combined Study Result

The significant improvement in the visual appearance of dry skin treated with
Bio‑Oil Skincare Oil (Natural) in study two confirms its effectiveness in relieving
dry and dehydrated skin. This is further supported with the improvements in
stratum corneum barrier function and transepidermal water loss in both studies.