Trial centre

proDERM Institute for Applied Dermatological Research, Hamburg, Germany.


To assess the efficacy of Bio‑Oil Skincare Oil (Natural) in improving the
appearance of scars.


Subjects: 40 female participants of varying ethnicities. Scar ages: newly formed
to 3 years old. Scar locations: face or body due to major grazes, cuts or surgical
scars. Age of participants: 18—65.


Evaluator blinded, randomised image assessment, open-label study. Subject
inclusion was performed by a dermatologist using the Patient and Observer Scar
Assessment Scale (POSAS). Bio‑Oil Skincare Oil (Natural) was applied twice
daily for 8 weeks by gently massaging in a circular motion on the assigned scar
and surrounding skin. Application was performed under supervision at regular
intervals. The main objective was to assess the effect of the product on the skin
investigated by means of POSAS at baseline, and at 2, 4 and 8 weeks. Further
parameters investigated at the end of the study included image assessment
of the aesthetic outcome by 6 trained assessors and subjects themselves,
and skin colour deviation of the scars to their surrounding as measured by a


Bio‑Oil Skincare Oil (Natural) is efficacious in improving the appearance of scars.
A statistically significant improvement in POSAS (considering both the objective
and subjective assessments of OSAS and PSAS) after only 2 weeks was evident
in 94% of the subjects. After 8 weeks 100% of subjects showed a noticeable
improvement, with the extent of the improvement more than double that at 2
weeks. A continuous and significant improvement of POSAS over the duration of
the study was noted.