Trial centre

Complife Italia S.r.l, Italy.

ObjectiveTo assess the potential of Bio‑Oil Skincare Oil (Natural) to cause skin irritation.


25 participants, 3 male and 22 female, all with sensitive skin according to lactic
acid stinging test. Age of participants: 18—70.


Controlled study. Two areas were evaluated: area to which a negative control
was applied (demineralised water) and an area to which Bio‑Oil Skincare Oil
(Natural) was applied. Test products were applied to the backs of participants, in
contact with the skin surface, for a period of 48 hours using a Fin chamber. Skin
reactions were evaluated under the supervision of a dermatologist, to assess
primary skin irritation at 15 minutes, 1 hour and 24 hours after patch removal.
Skin reactions were rated on a scale from 0—4 (with 0 being no erythema,
oedema, or other types of skin irritation, and 4 being serious erythema and
oedema, indicating dark red appearance and extended swelling and beyond the
application area).


The skin tolerability of Bio‑Oil Skincare Oil (Natural) was deemed ‘non-irritating’.