Striae study, 2010

Q: Striae study, 2010

Trial centre proDERM Institute for Applied Dermatological Research, Hamburg, Germany. Objective To assess the efficacy of Bio‑Oil Skincare Oil in improving the appearance of striae. Sample Subjects: 38 female participants of varying ethnicities. Striae causes: various (post pregnancy, weight gain or adolescent growth spurt). Striae locations: abdomen, thigh and hips. Age of participants: 18 to 65. Methodology Double-blind, randomised and placebo controlled. Subjects had matching striae or striae large enough to allow a half-half striae application and intrasubject comparison. Product was applied twice daily for 8 weeks, no additional massaging performed on the target area. Application performed under supervision at regular intervals. Assessments conducted at 0, 2, 4 and 8 weeks. Different scar parameters as defined in the Patient and Observer Scar Assessment Scale (POSAS) were evaluated. Result Bio‑Oil Skincare Oil is efficacious in improving the appearance of striae. A statistically significant result after only 2 weeks (day 15), evident in 95% of the subjects. After 8 weeks (day 57) 100% of subjects showed an improvement, with the extent of the improvement more than double that at 2 weeks. A continuous improvement of POSAS over the duration of the study.

Trial centre
proDERM Institute for Applied Dermatological Research, Hamburg, Germany.

Objective
To assess the efficacy of Bio‑Oil Skincare Oil in improving the appearance of striae.

Sample
Subjects: 38 female participants of varying ethnicities. Striae causes: various (post pregnancy, weight gain or adolescent growth spurt). Striae locations: abdomen, thigh and hips. Age of participants: 18 to 65.

Methodology
Double-blind, randomised and placebo controlled. Subjects had matching striae or striae large enough to allow a half-half striae application and intrasubject comparison. Product was applied twice daily for 8 weeks, no additional massaging performed on the target area. Application performed under supervision at regular intervals. Assessments conducted at 0, 2, 4 and 8 weeks. Different scar parameters as defined in the Patient and Observer Scar Assessment Scale (POSAS) were evaluated.

Result
Bio‑Oil Skincare Oil is efficacious in improving the appearance of striae. A statistically significant result after only 2 weeks (day 15), evident in 95% of the subjects. After 8 weeks (day 57) 100% of subjects showed an improvement, with the extent of the improvement more than double that at 2 weeks. A continuous improvement of POSAS over the duration of the study.