Trial centre
Thomas J. Stephens & Associates, Inc., Texas, United States of America
Objective
To evaluate the efficacy of Bio‑Oil Skincare Oil (Natural) in improving the
appearance of uneven skin tone and mottled pigmentation when used by women
with mild to moderate photodamaged (ageing) skin on the face and neck.
Sample
Subjects: 64 female participants of varying ethnicities with clinically determined
with mild to moderate photodamage on the face and neck. Bio‑Oil Skincare Oil
(Natural) treatment cell included 32 subjects and the untreated cell included 32
subjects. Age of participants: 30—70.
Methodology
Full-faced, randomised, controlled, efficacy grader-blinded study. Subjects
participated in an initial screening evaluation followed by a 1-week washout
period. For the treatment group, Bio‑Oil Skincare Oil (Natural) was applied to
the face and neck twice daily for 16 weeks, the initial application was performed
under supervision at the baseline visit. Clinical evaluations were conducted at
0, 2, 4 and 16 weeks. Subjects were clinically graded on the global face and
neck for uneven skin tone and mottled pigmentation. Digital images were also
taken of each subject’s face and neck, photo grading was performed after study
completion.
Result
Bio‑Oil Skincare Oil (Natural) is efficacious in improving the appearance of
uneven skin tone and mottled pigmentation on photodamaged (ageing) skin.
After 16 weeks a statistically significant result was achieved for both parameters 23
on the face and neck, according to clinical and photo grading. After 16 weeks,
61% and 57% of subjects in the Bio-Oil Skincare Oil (Natural) treatment cell
showed a statistically significant improvement in uneven skin tone and mottled
pigmentation respectively.
